
Dynamic covalent and Supramolecular biomaterials
Dynamic Covalent and Supramolecular Biomaterials
Living systems are in constant motion—building, breaking down, adapting, and healing in response to their environment. To emulate these complex behaviors, we develop biomaterials that are not static, but dynamic and life-like. By integrating dynamic covalent bonds and supramolecular interactions, we create materials that can respond, reorganize, and evolve—just like biological tissues.
Dynamic covalent bonds offer stability with the possibility of reversible exchange, while supramolecular interactions—based on reversible, non-covalent forces—enable rapid responsiveness and adaptability. These mechanisms allow materials to heal themselves, adapt to changing environments, and closely mimic the dynamic nature of biological systems.
At MERLN, we use these principles to design smart, functional materials that can communicate with cells, guide tissue regeneration, and respond to physiological cues over time. Our goal is to move beyond passive biomaterials and toward systems that truly behave like living matter—supporting and actively participating in the healing and regeneration process.