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Madina Sangen

PhD Student

Cartilage engineering using chemically modified mRNA

Madina holds a Bachelor's degree in Biomedical Laboratory Technology from University College Leuven Limburg and a Master's degree in Biomedical Sciences with a specialization in Regenerative Medicine from Maastricht University. For her Master’s thesis, she explored how amino acids influence the osteogenic potential of bone marrow mesenchymal stem cells. This research was conducted within the cBITE department of MERLN and the Department of Trauma Surgery at MUMC+.

In September 2022, Madina embarked on a double-degree PhD, working jointly with the MERLN Institute and the Department of Experimental Orthopaedics and Trauma Surgery at Uniklinik RWTH Aachen. Under the supervision of Prof. Dr. Martijn van Griensven and Prof. Dr. Elizabeth Rosado Balmayor, she is focusing on cartilage engineering through the innovative use of chemically modified RNA, addressing challenges of regenerating cartilage, a tissue with limited capacity for self-repair, which is a key factor in the development of diseases like osteoarthritis. Through mRNA therapy, Madina aims to develop innovative solutions that could revolutionize the treatment of cartilage-related conditions and contribute to the advancement of regenerative medicine.

Madina Sangen

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