Adam Stell

PhD Student

Creation of open design device for human islet transplantation

Adam had been carrying out various kinds of research as a research technician at a number of Universities throughout the United States, Sweden and the Netherlands for a number of years. Looking for a new challenge, he started a PhD in the department of Complex Tissue Regeneration (CTR) MERLN in April of 2016. With a focus on islet physiology, he is working towards developing an implantable device to better protect human islets that are being transplanted into Type I diabetics to treat their condition.
As the current procedures calls for delivering a mass of islets into the patient’s liver, this results in the death of a large proportion of the islets within three days of transplantation because of innate immune responses, hypoxia and toxicity of the environment. An open device containing a lesser quantity of islets, placed in a less hostile environment, should result in a better outcome for the islets and a long-term benefit for the patient.

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