David Koper

PhD Student

Development of Instructive Composite Biomaterials for Cranio-Maxillofacial Skeletal Regeneration

David studied medicine at Maastricht University, and subsequently studied dentistry at Radboud University Nijmegen, after which he specialised as a Cranio-Maxillofacial Surgeon (CMF-surgeon) at Maastricht University Medical Center and the Elkerliek Hospital in Helmond.
Already early during his studies, he started clinical research focusing on Patient-Specific Implants (PSIs) and Additive Manufacturing (AM) technologies in CMF-surgery. Implants currently used in clinical practice, for instance to reconstruct large skull bone defects, are well accepted by the body, but they lack an active interaction with the surrounding tissues, and therefore implant failure may occur. It is clear that a need exists to improve the bioactivity of these implants. In his PhD project, David aims to develop PSIs for the regeneration of CMF bone defects with significantly improved bioactivity compared to the currently available implants, by using novel composite biomaterials that are processed by employing additive manufacturing technologies. He will evaluate the newly developed implants both in vitro and in vivo.