Silvia Crasto


Endocrine disruptors screening in 3D models of thyroid organoids and engineered thyroid constructs

Silvia graduated from University of Federico II in Naples (Italy) where she received her BSc in Biology. She obtained her MSc in Molecular Biology at the University of Milano Bicocca and she did her master thesis internship at the European Institute of Oncology (IEO) in Milan (Italy).

Silvia did her PhD in Immunology and Immunopathology at The Open University, care of Humanitas Research Centre, Cardiovascular Department (Milan, Italy). Her PhD project aimed to investigate molecular mechanisms of Lamin A/C and its mutations in human iPSC-derived cardiomyocytes and to define how Lamin A/C regulates chromatin organization, gene transcription and cardiomyocytes functionality. During her doctoral program, to increase her knowledge and skills in the microscopy field, she attended the EMBL course on STED super resolution microscopy in Heidelberg (Germany). As of February 2021, Silvia is working in MERLN as a Postdoc at the CTR Department on screening for endocrine disruptors in 3D murine and human pluripotent stem cells (PSCs) – derived Thyroid Follicles models.

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