Publications 2021
- Amann, E., Amirall, A., Franco, A. R., Poh, P. S. P., Sola Dueñas, F. J., Fuentes Estévez, G., Leonor, I. B., Reis, R. L., van Griensven, M., Balmayor, E. R. (2021). A graded, porous composite of natural biopolymers and octacalcium phosphate guides osteochondral differentiation of stem cells. Advanced Healthcare Materials, 10(6), [2001692]. https://doi.org/10.1002/adhm.202001692
- Anand, S., Stoppe, T., Lucena, M., Rademakers, T., Neudert, M., Danti, S., Moroni, L., Mota, C. (2021). Mimicking the Human Tympanic Membrane: The Significance of Scaffold Geometry. Advanced Healthcare Materials, 10(11), [e2002082]. https://doi.org/10.1002/adhm.202002082
- Bauer, J. (2021). Teaching Nanotechnology through Research Proposals. Journal of Chemical Education, 98(7), 2347-2355. https://doi.org/10.1021/acs.jchemed.0c01251
- Biberthaler, P., van Griensven, M. (2021). Pseudarthrosen. In: Orthopädie und Unfallchirurgie. (pp. 1-11). Springer. https://doi.org/10.1007/978-3-642-54673-0_43-1
- Català, P., Groen, N., Dehnen, J. A., Soares, E., van Velthoven, A. J. H., Nuijts, R. M. M. A., Dickman, M., LaPointe, V. L. S. (2021). Single cell transcriptomics reveals the heterogeneity of the human cornea to identify novel markers of the limbus and stroma. Scientific Reports, 11, [21727]. https://doi.org/10.1038/s41598-021-01015-w
- Català, P., Thuret, G., Skottman, H., Mehta, J. S., Parekh, M., Dhubhghaill, S. N., Collin, R. W. J., Nuijts, R. M. M. A., Ferrari, S., LaPointe, V. L. S., Dickman, M. (2021). Approaches for corneal endothelium regenerative medicine. Progress in Retinal and Eye Research, In Press. https://doi.org/10.1016/j.preteyeres.2021.100987
- Cerny, M. K., Wiesmeier, A., Hopfner, U., Topka, C., Zhang, W., Machens, H., van Griensven, M., Broer, N., Duscher, D. Wound fluid under occlusive dressings from diabetic patients show an increased angiogenic response and fibroblast migration. Journal of Tissue Viability, 30(3), 446-453. https://doi.org/10.1016/j.jtv.2021.02.013
- De la Vega, R. E., Atasoy-Zeybek, A., Panos, J., van Griensven, M., Evans, C. H., Balmayor, E. R. (2021). Gene Therapy for Bone Healing: Lessons Learned and New Approaches. Translational Research, 236, 1-16. https://doi.org/10.1016/j.trsl.2021.04.009
- Decarli, M. C., Amaral, R. L. F., Dos Santos, D. P., Tofani, L. B., Katayama, E., Rezende, R. A., Silva, J. V. L. D., Swiech, K., Suazo, C. A. T., Mota, C., Moroni, L., Moraes, Â. M. (2021). Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications. Biofabrication, 13(3), [032002]. https://doi.org/10.1088/1758-5090/abe6f2
- Eroumé, K., Cavill, R., Stankova, K., de Boer, J., Carlier, A. (2021). Exploring the influence of cytosolic and membrane FAK activation on YAP/TAZ nuclear translocation. Biophysical Journal, In Press. https://doi.org/10.1016/j.bpj.2021.09.009
- Eroumé, K., Vasilevich, A., Vermeulen, S., de Boer, J., Carlier, A. (2021). On the influence of cell shape on dynamic reaction-diffusion polarization patterns. PLoS ONE, 16(3), [e0248293]. https://doi.org/10.1371/journal.pone.0248293
- Fayed, O., van Griensven, M., Birgani, Z. T., Plank, C., Balmayor, E. R. (2021). Transcript-activated coatings on titanium mediate cellular osteogenesis for enhanced osteointegration. Molecular Pharmaceutics, 18(3), 1121-1137. https://doi.org/10.1021/acs.molpharmaceut.0c01042
- Feliciano, A. J., van Blitterswijk, C., Moroni, L. Baker, M. B. (2021). Realizing tissue integration with supramolecular hydrogels. Acta Biomaterialia, 124, 1-14. https://doi.org/10.1016/j.actbio.2021.01.034
- Fischer, J. C., Schmidt, A. G., Boelke, E., Uhrberg, M., Keitel, V., Feldt, T., Jensen, B., Häussinger, D., Adams, O., Schneider, E. M., Balz, V., Enczmann, J., Rox, J., Hermsen, D., Schulze-Bosse, K., Kindgen-Milles, D., Knoefel, W. T., van Griensven, M., Haussmann, J., Tamaskovics, B., Plettenberg, C., Scheckenbach, K., Corradini, S., Pedoto, A., Maas, K., Schmidt, L., Grebe, O., Esposito, I., Erhardt, A., Peiper, M., Buhren, B. A., Calles, C., Stöhr, A., Lichtenberg, A., Freise, N., Lutterbeck, M., Rezazadeh, A., Budach, W., Matuschek, C. (2021). Association of HLA genotypes, AB0 blood type and chemokine receptor 5 mutant CD195 with the clinical course of COVID-19. European Journal of Medical Research, 26, [107]. https://doi.org/10.1186/s40001-021-00560-4
- Formisano, N., Sahin, G., Català, P., Truckenmüller, R., Nuijts, R. M. M. A., Dickman, M. M., LaPointe, V. L. S., Giselbrecht, S. (2021). Nanoscale topographies for corneal endothelial regeneration. Applied Science, 11, [827]. https://doi.org/10.3390/app11020827
- Fransen, M. F. J., Addario, G., Bouten, C. V. C., Halary, F., Moroni, L., Mota, C. (2021). Bioprinting of kidney in vitro models: cells, biomaterials, and manufacturing techniques. Essays in Biochemistry, [EBC20200158]. https://doi.org/10.1042/EBC20200158
- Galván-Chacón, V. P., Costa, L., Barata, D., Habibovic, P. (2021). Droplet microfluidics as a tool for production of bioactive calcium phosphate microparticles with controllable physicochemical properties. Acta Biomaterialia, 128, 486-501. https://doi.org/10.1016/j.actbio.2021.04.029
- Geuens, T., Ruiter, F. A. A., Schumacher, A., Morgan, F. L. C., Rademakers, T., Wiersma, L. E., van den Berg, C. W., Rabelink, T. J., Baker, M. B., LaPointe, V. L. S. (2021). Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition. Biomaterials, 275, [120976]. https://doi.org/10.1016/j.biomaterials.2021.120976
- Gottardi, R., Moeller, K., Di Gesù, R., Tuan, R. S., van Griensven, M., Balmayor, E. R. (2021). Application of a hyperelastic 3D printed scaffold for mesenchymal stem cell-based fabrication of a bizonal tendon enthesis-like construct. Frontiers in Materials, 8, [613212]. https://doi.org/10.3389/fmats.2021.613212
- Groven, R. V. M., van Koll, J., Poeze, M., Blokhuis, T. J., van Griensven, M. (2021). miRNAs Related to Different Processes of Fracture Healing: An Integrative Overview. Frontiers in Surgery, 8, [786564]. https://doi.org/10.3389/fsurg.2021.786564
- Guttenplan, A. P. M., Bormans, S., Birgani, Z. T., Schumacher, M., Giselbrecht, S., Truckenmüller, R. K., Habibovic, P., Thoelen, R. (2021). Measurement of biomimetic deposition of calcium phosphate in real time using complex capacitance. Physica Status Solidi A, In Press. https://doi.org/10.1002/pssa.202000672
- Guttenplan, A. P. M., Tahmasebi Birgani, Z., Giselbrecht, S., Truckenmüller, R. K., Habibović, P. (2021). Chips for Biomaterials and Biomaterials for Chips: Recent Advances at the Interface between Microfabrication and Biomaterials Research. Advanced Healthcare Materials, [2100371]. https://doi.org/10.1002/adhm.202100371
- Hadavi, E., de Vries, R. H. W., Smink, A. M., de Haan, B., Leijten, J., Schwab, L. W., Karperien, M. H. B. J., de Vos, P., Dijkstra, P. J., van Apeldoorn, A. A. (2021). In vitro degradation profiles and in vivo biomaterial–tissue interactions of microwell array delivery devices. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 109(1), 117-127. https://doi.org/10.1002/jbm.b.34686
- Haupt, J., Krysiak, N., Unger, M., Bogner-Flatz, V., Biberthaler, P., Hanschen, M., van Griensven, M., Haug, A. T. (2021). The potential of adipokines in identifying multiple trauma patients at risk of developing multiple organ dysfunction syndrome. European Journal of Medical Research, 26(1), [38]. https://doi.org/10.1186/s40001-021-00511-z
- Hoff, N., Freise, N., Schmidt, A., Firouzi-Memarpuri, P., Reifenberger, J., Lüdde, T., Boelke, E., Meller, S., Homey, B., Feldt, T., Jensen, B., Keitel, V., Schmidt, L., Maas, K., Haussmann, J., Tamaskovics, B., Budach, W., Fischer, J., Buhren, B., Knoefel, W., Schneider, M., Gerber, P., Pedotoa, A. Häussinger, D., Grebe, O., van Griensven, M., Salzmann, S., Braun, S., Rezazadeh, A., Matuschek, C. (2021). Delayed skin reaction after mRNA‑1273 vaccine against SARS‑CoV‑2: a rare clinical reaction. European Journal of Medical Research, 26, [98]. https://doi.org/10.1186/s40001-021-00557-z
- Karagöz, Z., Geuens, T., LaPointe, V. L. S., van Griensven, M., Carlier, A. (2021). Win, lose, or tie: Mathematical modeling of ligand competition at the cell–extracellular matrix interface. Frontiers in Bioengineering and Biotechnology, 9, [657244]. https://doi.org/10.3389/fbioe.2021.657244
- Karagöz, Z., Rijns, L., Dankers, P. Y. W., van Griensven, M., Carlier, A. (2021). Towards understanding the messengers of extracellular space: Computational models of outside-in integrin reaction networks. Computational and Structural Biotechnology Journal, 19, 303-314. https://doi.org/10.1016/j.csbj.2020.12.025
- Karel, M. F. A., Lemmens, T. P., Tullemans, B. M. E., Wielders, S. J. H., Gubbins, E., van Beurden, D., van Rijt, S., Cosemans, J. M. E. M. (2021). Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays. Cellular and Molecular Bioengineering, In Press. https://doi.org/10.1007/s12195-021-00713-9
- King, J., Eroumé, K. S., Truckenmüller, R., Giselbrecht, S., Cowan, A. E., Loew, L., Carlier, A. (2021). Ten steps to investigate a cellular system with mathematical modeling. PLoS Computational Biology, 17(5), [e1008921]. https://doi.org/10.1371/journal.pcbi.1008921
- King, J., Mihaila, S., Ahmed, S., Truckenmüller, R., Giselbrecht, S., Masereeuw, R., Carlier, A. (2021). The influence of OAT1 density and functionality on indoxyl sulfate transport in the human proximal tubule: an integrated computational and in vitro study. Toxins, 13(10), [674]. https://doi.org/10.3390/toxins13100674
- King, J., Swapnasrita, S., Truckenmüller, R., Giselbrecht, S., Masereeuw, R., Carlier, A. (2021). Modeling indoxyl sulfate transport in a bioartificial kidney: two-step binding kinetics or lumped parameters for uremic toxin clearance? Computers in Biology and Medicine, In Press. https://doi.org/10.1016/j.compbiomed.2021.104912
- Li, J., Yuan, H., Chandrakar, A., Moroni, L., Habibovic, P. (2021). 3D porous Ti6Al4V-beta-tricalcium phosphate scaffolds directly fabricated by additive manufacturing. Acta Biomaterialia, 126, 496-510. https://doi.org/10.1016/j.actbio.2021.03.021
- López De Padilla, C. M., Coenen, M. J., Tovar, A., De la Vega, R. E., Evans, C. H., Müller, S. A. (2021). Picrosirius Red Staining: Revisiting Its Application to the Qualitative and Quantitative Assessment of Collagen Type I and Type III in Tendon. Journal of Histochemistry and Cytochemistry, In Press. https://doi.org/10.1369%2F00221554211046777
- Madry, H., Grässel, S., Nöth, U., Relja, B., Bernstein, A., Docheva, D., Kauther, M. D., Katthagen, J. C., Bader, R., van Griensven, M., Wirtz, D. C., Raschke, M. J., Huber-Lang, M. (2021). The future of basic science in orthopaedics and traumatology: Cassandra or Prometheus? European Journal of Medical Research, 26(1), [56]. https://doi.org/10.1186/s40001-021-00521-x
- Margarida Carvalho, A., Paulino da Silva Filho, O., van Apeldoorn, A. (2021). Protection factors used to improve in vivo islet function. Journal of Immunology and Regenerative Medicine, In Press. https://doi.org/10.1016/j.regen.2021.100051
- Paradise, C. R., De La Vega, R. E., Lizeth Galvan, M., Carrasco, M. E., Thaler, R., van Wijnen, A. J., Dudakovic, A. (2021). Brd4 Inactivation Increases Adenoviral Delivery of BMP2 for Paracrine Stimulation of Osteogenic Differentiation as a Gene Therapeutic Concept to Enhance Bone Healing. JBMR Plus, [e10520]. https://doi.org/10.1002/jbm4.10520
- Passanha, F. R., Geuens, T., LaPointe, V. L. S. (2021). Sticking Together: Harnessing Cadherin Biology for Tissue Engineering. Acta Biomaterialia, In Press. https://doi.org/10.1016/j.actbio.2021.07.070
- Passanha, F. R., Gomes, D. B., Piotrowska, J., Students of PRO3011, Moroni, L., Baker, M. B., LaPointe, V. L. S. (2021). A comparative study of mesenchymal stem cells cultured as cell-only aggregates and in encapsulated hydrogels. Journal of Tissue Engineering and Regenerative Medicine, In Press. https://doi.org/10.1002/term.3257
- Payr, S., Rosado-Balmayor, E., Tiefenboeck, T., Schuseil, T., Unger, M., Seeliger, C., van Griensven, M. (2021). Direct comparison of 3D and 2D cultivation reveals higher osteogenic capacity of elderly osteoblasts in 3D. 16, [13]. https://doi.org/10.1186/s13018-020-02153-z
- Pereira, D. D. M., Schumacher, M., Habibovic, P. (2021). Cobalt-containing calcium phosphate induces resorption of biomineralized collagen by human osteoclasts. Biomaterials Research, 25, [6]. https://doi.org/10.21203/rs.3.rs-136339/v1
- Reys, L. L., Vaithilingam, V., Sthijns, M. M. J. P. E., Soares, E., Rademakers, T., de Vries, R., Mohammed, S., de Bont, D., Jetten, M., Hermanns, C., da Silva Filho, O., Stell, A., Mourad, N. I., Gianello, P., LaPointe, V. L. S., Silva, S. S., Reis, R. L., Silva, T. H., van Apeldoorn, A. (2021). Fucoidan hydrogels significantly alleviate oxidative stress and enhance the endocrine function of encapsulated beta cells. Advanced Functional Materials, In Press. https://doi.org/10.1002/adfm.202011205
- Schumacher, A., Rookmaaker, M. M., Joles, J. A., Kramann, R., Nguyen, T. Q., van Griensven, M., LaPointe, V. L. S. (2021). Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing. NPJ Regenerative Medicine, 6(1), [45]. https://doi.org/10.1038/s41536-021-00156-w
- Schumacher, M., Habibovic, P., van Rijt, S. (2021). Mesoporous bioactive glass composition effects on degradation and bioactivity. Bioactive Materials, 6(7), 1921-1931. https://doi.org/10.1016/j.bioactmat.2020.12.007
- Shankar, V., van Blitterswijk, C., Vrij, E., Giselbrecht, S. (2021). From Snapshots to Development: Identifying the Gaps in the Development of Stem Cell‐based Embryo Models along the Embryonic Timeline. Advanced Science, [2004250]. https://doi.org/10.1002/advs.202004250
- Sinha, R., Cámara-Torres, M., Scopece, P., Verga Falzacappa, E., Patelli, A., Moroni, L., Mota, C. (2021). A hybrid additive manufacturing platform to create bulk and surface composition gradients on scaffolds for tissue regeneration. Nature Communications, 12, [500]. https://doi.org/10.1038/s41467-020-20865-y
- Sthijns, M. M. J. P. E., Jetten, M. J., Mohammed, S. G., Claessen, S. M. H., de Vries, R. H. W., Stell, A., de Bont, D. F. A., Engelse, M. A., Mumcuoglu, D., van Blitterswijk, C. A., Dankers, P. Y. W., de Koning, E. J. P., van Apeldoorn, A. A., LaPointe, V. L. S. (2021). Oxidative stress in pancreatic alpha and beta cells as a selection criterion for biocompatible biomaterials. Biomaterials, 267, [120449]. https://doi.org/10.1016/j.biomaterials.2020.120449
- Sutthavas, P., Habibovic, P., van Rijt, S. H. (2021). The shape-effect of calcium phosphate nanoparticle based films on their osteogenic properties. Biomaterials Science, 9(5), 1754-1766. https://doi.org/10.1039/D0BM01494J
- Sutthavas, P., Tahmasebi Birgani, Z., Habibovic, P., van Rijt, S. (2021). Calcium Phosphate Coated and Strontium Incorporated Mesoporous Silica Nanoparticles can Effectively Induce Osteogenic Stem Cell Differentiation. Advanced Healthcare Materials, In Press. https://doi.org/10.1002/adhm.202101588
- Tellado, S. F., Delgado, J. A., Poh, S. P. P., Zhang, W., García-Vallés, M., Martínez, S., Gorustovich, A., Morejón, L., van Griensven, M., Balmayor, E. R. (2021). Phosphorous pentoxide-free bioactive glass exhibits dose-dependent angiogenic and osteogenic capacities which are retained in glass polymeric composite scaffolds. Biomaterials Science, In Press. https://doi.org/10.1039/D1BM01311D
- Vaes, J. E. G., van Kammen, C. M., Trayford, C., van der Toorn, A., Ruhwedel, T., Benders, M. J. N. L., Dijkhuizen, R. M., Möbius, W., van Rijt, S. H., Nijboer, C. H. (2021). Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity. Glia, 69(3), 655-680. https://doi.org/10.1002/glia.23919
- van Velthoven, A. J. H., Bertolin, M., Barbaro, V., Sthijns, M. M. J. P. E., Nuijts, R. M. M. A., LaPointe, V. L. S., Dickman, M. M., Ferrari, S. (2021). Increased Cell Survival of Human Primary Conjunctival Stem Cells in Dimethyl Sulfoxide-Based Cryopreservation Media. Biopreservation and Biobanking, 19(1), 67-72. https://doi.org/10.1089/bio.2020.0091
- Vermeulen, S., Honig, F., Vasilevich, A., Roumans, N., Romero, M., Dede Eren, A., Tuvshindorj, U., Alexander, M., Carlier, A., Williams, P., Uquillas, J., de Boer, J. (2021). Expanding Biomaterial Surface Topographical Design Space through Natural Surface Reproduction. Advanced Materials, [e2102084]. https://doi.org/10.1002/adma.202102084
- Viguerie, A., Swapnasrita, S., Veneziani, A., Carlier, A. (2021). A multi-domain shear-stress dependent diffusive model of cell transport-aided dialysis: analysis and simulation. Mathematical Biosciences and Engineering, 18(6), 8188-8200. https://doi.org/10.3934/mbe.2021406
- Wieland, F. C., Sthijns, M. M. J. P. E., Geuens, T., van Blitterswijk, C. A., LaPointe, V. L. S. (2021). The Role of Pancreatic Alpha Cells and Endothelial Cells in the Reduction of Oxidative Stress in Pseudoislets. Frontiers in Bioengineering and Biotechnology, 9, [729057]. https://doi.org/10.3389/fbioe.2021.729057
- Wieland, F. C., van Blitterswijk, C. A., van Apeldoorn, A., LaPointe, V. L. S. (2021). The functional importance of the cellular and extracellular composition of the islets of Langerhans. Journal of Immunology and Regenerative Medicine, [100048]. https://doi.org/10.1016/j.regen.2021.100048
- Yang, L., Pijuan-Galito, S., Rho, H. S., Vasilevich, A. S., Eren, A. D., Ge, L., Habibovic, P., Alexander, M. R., de Boer, J., Carlier, A., van Rijn, P., Zhou, Q. (2021). High-throughput methods in the discovery and study of biomaterials and materiobiology. Chemical Reviews, 121(8), 4561–4677. https://doi.org/10.1021/acs.chemrev.0c00752
- Zengin, A., Castro, J. P. O., Habibovic, P., van Rijt, S. H. (2021). Injectable, self-healing mesoporous silica nanocomposite hydrogels with improved mechanical properties. Nanoscale, 13(2), 1144-1154. https://doi.org/10.1039/D0NR07406C
- Zhang, Y., Li, J., Mouser, V. H. M., Roumans, N., Moroni, L., Habibovic, P. (2021). Biomimetic Mechanically Strong One-Dimensional Hydroxyapatite/Poly(d,l-lactide) Composite Inducing Formation of Anisotropic Collagen Matrix. ACS Nano, In Press. https://doi.org/10.1016/j.actbio.2021.06.044
- Zhang, Y., Li, J., Soleimani, M., Giacomini, F., Friedrich, H., Truckenmüller, R., Habibovic, P., (2021). Biodegradable Elastic Sponge from Nanofibrous Biphasic Calcium Phosphate Ceramic as an Advanced Material for Regenerative Medicine. Advanced Functional Materials, In Press. https://doi.org/10.1021/acsnano.1c03905
- Zhang, X., van Rijt, S. (2021). 2D biointerfaces to study stem cell–ligand interactions. Acta Biomaterialia, In Press. https://doi.org/10.1016/j.actbio.2021.06.044