• Recent publications

Publications 2016

  • Malhotra, A., & Habibovic, P. (2016). Calcium Phosphates and Angiogenesis: Implications and Advances for Bone Regeneration. Trends in Biotechnology, 34(12), 983-992. https://doi.org/10.1016/j.tibtech.2016.07.005
  • Potier, E., Rivron, N. C., Van Blitterswijk, C. A., & Ito, K. (2016). Micro-aggregates do not influence bone marrow stromal cell chondrogenesis. Journal of Tissue Engineering and Regenerative Medicine, 10(12), 1021-1032. https://doi.org/10.1002/term.1887
  • Di Luca, A., Longoni, A., Criscenti, G., Mota, C., van Blitterswijk, C., & Moroni, L. (2016). Toward mimicking the bone structure: design of novel hierarchical scaffolds with a tailored radial porosity gradient. Biofabrication, 8(4), [045007]. https://doi.org/10.1088/1758-5090/8/4/045007
  • Duan, R., Barbieri, D., Luo, X., Weng, J., de Bruijn, J. D., & Yuan, H. (2016). Submicron-Surface Structured Tricalcium Phosphate Ceramic Enhances the Bone Regeneration in Canine Spine Environment. Journal of Orthopaedic Research, 34(11), 1865-1873. https://doi.org/10.1002/jor.23201
  • Garzoni, M., Baker, M. B., Leenders, C. M. A., Voets, I. K., Albertazzi, L., Palmans, A. R. A., ... Pavan, G. M. (2016). Effect of H-Bonding on Order Amplification in the Growth of a Supramolecular Polymer in Water. Journal of the American Chemical Society, 138(42), 13985-13995. https://doi.org/10.1021/jacs.6b07530
  • Baker, M. B., Ferreira, R. B., Tasseroul, J., Lampkins, A. J., Al Abbas, A., Abboud, K. A., & Castellano, R. K. (2016). Selective and Sequential Aminolysis of Benzotrifuranone: Synergism of Electronic Effects and Ring Strain Gradient. Journal of Organic Chemistry, 81(19), 9279-9288. https://doi.org/10.1021/acs.joc.6b01867
  • Moroni, L. (2016). Tempo: timing & metamorphosis in biofabrication. Maastricht: Maastricht University. https://doi.org/10.26481/spe.20161006lm
  • Zhou, Y., Xiao, Y., Qiu, Y., Yuan, H., van Blitterswijk, C. A., Zhou, X., ... Bao, C. (2016). Adhesion and proliferation of cells and bacteria on microchip with different surfaces microstructures. Biomedizinische Technik, 61(5), 475-482. https://doi.org/10.1515/bmt-2015-0075
  • Malheiro, A., Wieringa, P., Mota, C., Baker, M., & Moroni, L. (2016). Patterning Vasculature: The Role of Biofabrication to Achieve an Integrated Multicellular Ecosystem. ACS Biomaterial Science and Engineering, 2(10), 1694-1709. https://doi.org/10.1021/acsbiomaterials.6b00269
  • Rothuizen, T. C., Kemp, R., Duijs, J. M. G. J., de Boer, H. C., Bijkerk, R., van der Veer, E. P., ... Rotmans, J. I. (2016). Promoting Tropoelastin Expression in Arterial and Venous Vascular Smooth Muscle Cells and Fibroblasts for Vascular Tissue Engineering. Tissue Engineering. Part C. Methods , 22(10), 923-931. https://doi.org/10.1089/ten.tec.2016.0173
  • Sun, L., Danoux, C. B., Wang, Q., Pereira, D., Barata, D., Zhang, J., ... Habibovic, P. (2016). Independent effects of the chemical and microstructural surface properties of polymer/ceramic composites on proliferation and osteogenic differentiation of human MSCs. Acta Biomaterialia, 42, 364-377. https://doi.org/10.1016/j.actbio.2016.06.018
  • Nibbelink, M. G., Marchioli, G., Moroni, L., Karperien, M., & Van Apeldoorn, A. (2016). A Protocol to Enhance INS1E and MIN6 FunctionalityThe Use of Theophylline. International Journal of Molecular Sciences, 17(9), [1532]. https://doi.org/10.3390/ijms17091532
  • Sun, L., Pereira, D., Wang, Q., Barata, D., Truckenmuller, R., Li, Z., ... Habibovic, P. (2016). Controlling Growth and Osteogenic Differentiation of Osteoblasts on Microgrooved Polystyrene Surfaces. PLOS ONE, 11(8), [e0161466]. https://doi.org/10.1371/journal.pone.0161466
  • Carlier, A., & Alsberg, E. (2016). Harnessing Topographical Cues for Tissue Engineering. TISSUE ENGINEERING PART A, 22(15-16), 995-996. https://doi.org/10.1089/ten.tea.2016.0188
  • Birgani, Z. T., Malhotra, A., van Blitterswijk, C. A., & Habibovic, P. (2016). Human mesenchymal stromal cells response to biomimetic octacalcium phosphate containing strontium. Journal of Biomedical Materials Research Part A, 104(8), 1946-1960. https://doi.org/10.1002/jbm.a.35725
  • Leferink, A. M., Hendrikson, W. J., Rouwkema, J., Karperien, M., van Blitterswijk, C. A., & Moroni, L. (2016). Increased cell seeding efficiency in bioplotted three-dimensional PEOT/PBT scaffolds. Journal of Tissue Engineering and Regenerative Medicine, 10(8), 679-689. https://doi.org/10.1002/term.1842
  • Leferink, A. M., van Blitterswijk, C. A., & Moroni, L. (2016). Methods of Monitoring Cell Fate and Tissue Growth in Three-Dimensional Scaffold-Based Strategies for In Vitro Tissue Engineering. Tissue Engineering - Part B: Reviews, 22(4), 265-283. https://doi.org/10.1089/ten.teb.2015.0340
  • Danoux, C., Pereira, D., Dobelin, N., Stahli, C., Barralet, J., van Blitterswijk, C., & Habibovic, P. (2016). The Effects of Crystal Phase and Particle Morphology of Calcium Phosphates on Proliferation and Differentiation of Human Mesenchymal Stromal Cells. Advanced Healthcare Materials, 5(14), 1775-1785. https://doi.org/10.1002/adhm.201600184
  • Di Luca, A., Lorenzo-Moldero, I., Mota, C., Lepedda, A., Auhl, D., Van Blitterswijk, C., & Moroni, L. (2016). Tuning Cell Differentiation into a 3D Scaffold Presenting a Pore Shape Gradient for Osteochondral Regeneration. Advanced Healthcare Materials, 5(14), 1753-1763. https://doi.org/10.1002/adhm.201600083
  • Marchioli, G., Di Luca, A., de Koning, E., Engelse, M., Van Blitterswijk, C. A., Karperien, M., ... Moroni, L. (2016). Hybrid Polycaprolactone/Alginate Scaffolds Functionalized with VEGF to Promote de Novo Vessel Formation for the Transplantation of Islets of Langerhans. Advanced Healthcare Materials, 5(13), 1606-1616. https://doi.org/10.1002/adhm.201600058
  • Vrij, E., Rouwkema, J., LaPointe, V., van Blitterswijk, C., Truckenmuller, R., & Rivron, N. (2016). Directed Assembly and Development of Material-Free Tissues with Complex Architectures. Advanced Materials, 28(21), 4032-4039. https://doi.org/10.1002/adma.201505723
  • Neves, S. C., Mota, C., Longoni, A., Barrias, C. C., Granja, P. L., & Moroni, L. (2016). Additive manufactured polymeric 3D scaffolds with tailored surface topography influence mesenchymal stromal cells activity. Biofabrication, 8(2), [025012]. https://doi.org/10.1088/1758-5090/8/2/025012
  • Carlier, A., Skvortsov, G. A., Hafezi, F., Ferraris, E., Patterson, J., Koc, B., & Van Oosterwyck, H. (2016). Computational model-informed design and bioprinting of cell-patterned constructs for bone tissue engineering. Biofabrication, 8(2), [025009]. https://doi.org/10.1088/1758-5090/8/2/025009
  • Gazquez, G. C., Chen, H., Veldhuis, S. A., Solmaz, A., Mota, C. M. D., Boukamp, B. A., ... Moroni, L. (2016). Flexible Yttrium-Stabilized Zirconia Nanofibers Offer Bioactive Cues for Osteogenic Differentiation of Human Mesenchymal Stromal Cells. ACS Nano, 10(6), 5789-5799. https://doi.org/10.1021/acsnano.5b08005
  • Wuchter, P., Saffrich, R., Giselbrecht, S., Nies, C., Lorig, H., Kolb, S., ... Gottwald, E. (2016). Microcavity arrays as an in vitro model system of the bone marrow niche for hematopoietic stem cells. Cell and Tissue Research, 364(3), 573-584. https://doi.org/10.1007/s00441-015-2348-8
  • Richter, C., Kotz, F., Giselbrecht, S., Helmer, D., & Rapp, B. E. (2016). Numerics made easy: solving the Navier-Stokes equation for arbitrary channel cross-sections using Microsoft Excel. Biomedical Microdevices, 18(3), [52]. https://doi.org/10.1007/s10544-016-0070-2
  • van Oirschot, B. A. J. A., Eman, R. M., Habibovic, P., Leeuwenburgh, S. C. G., Tahmasebi, Z., Weinans, H., ... van den Beucken, J. J. J. P. (2016). Osteophilic properties of bone implant surface modifications in a cassette model on a decorticated goat spinal transverse process. Acta Biomaterialia, 37, 195-205. https://doi.org/10.1016/j.actbio.2016.03.037
  • Martin, I., De Boer, J., & Sensebe, L. (2016). A relativity concept in mesenchymal stromal cell manufacturing. Cytotherapy, 18(5), 613-620. https://doi.org/10.1016/j.jcyt.2016.02.004
  • Portalska, K. J., Chamberlain, M. D., Khor, C-C., van Blitterswijk, C., Sefton, M. V., & de Boer, J. (2016). Collagen modules for in situ delivery of mesenchymal stromal cell-derived endothelial cells for improved angiogenesis. Journal of Tissue Engineering and Regenerative Medicine, 10(5), 363-373. https://doi.org/10.1002/term.1738
  • Di Luca, A., Szlazak, K., Lorenzo-Moldero, I., Ghebes, C. A., Lepedda, A., Swieszkowski, W., ... Moroni, L. (2016). Influencing chondrogenic differentiation of human mesenchymal stromal cells in scaffolds displaying a structural gradient in pore size. Acta Biomaterialia, 36, 210-219. https://doi.org/10.1016/j.actbio.2016.03.014
  • Birgani, Z. T., Fennema, E., Gijbels, M. J., de Boer, J., van Blitterswijk, C. A., & Habibovic, P. (2016). Stimulatory effect of cobalt ions incorporated into calcium phosphate coatings on neovascularization in an in vivo intramuscular model in goats. Acta Biomaterialia, 36, 267-276. https://doi.org/10.1016/j.actbio.2016.03.031
  • Schilders, K. A. A., Eenjes, E., van Riet, S., Poot, A. A., Stamatialis, D., Truckenmuller, R., ... Rottier, R. J. (2016). Regeneration of the lung: Lung stem cells and the development of lung mimicking devices. Respiratory Research, 17, [44]. https://doi.org/10.1186/s12931-016-0358-z
  • Hardt, C., Beber, M. E., Rasche, A., Kamburov, A., Hebels, D. G., Kleinjans, J. C., & Herwig, R. (2016). ToxDB: pathway-level interpretation of drug-treatment data. Database-The Journal of Biological Databases and Curation, 2016, [baw052]. https://doi.org/10.1093/database/baw052
  • Barata, D., van Blitterswijk, C., & Habibovic, P. (2016). High-throughput screening approaches and combinatorial development of biomaterials using microfluidics. Acta Biomaterialia, 34, 1-20. https://doi.org/10.1016/j.actbio.2015.09.009
  • Groen, N., Guvendiren, M., Rabitz, H., Welsh, W. J., Kohn, J., & de Boer, J. (2016). Stepping into the omics era: Opportunities and challenges for biomaterials science and engineering. Acta Biomaterialia, 34, 133-142. https://doi.org/10.1016/j.actbio.2016.02.015
  • Ostrowska, B., Di Luca, A., Moroni, L., & Swieszkowski, W. (2016). Influence of internal pore architecture on biological and mechanical properties of three-dimensional fiber deposited scaffolds for bone regeneration. Journal of Biomedical Materials Research Part A, 104(4), 991-1001. https://doi.org/10.1002/jbm.a.35637
  • Di Luca, A., Ostrowska, B., Lorenzo-Moldero, I., Lepedda, A., Swieszkowski, W., Van Blitterswijk, C., & Moroni, L. (2016). Gradients in pore size enhance the osteogenic differentiation of human mesenchymal stromal cells in three-dimensional scaffolds. Scientific Reports, 6, [22898]. https://doi.org/10.1038/srep22898
  • Danoux, C., Sun, L., Kocer, G., Birgani, Z. T., Barata, D., Barralet, J., ... Habibovic, P. (2016). Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties. Advanced Materials, 28(9), 1803-1808. https://doi.org/10.1002/adma.201504589
  • Groll, J., Boland, T., Blunk, T., Burdick, J. A., Cho, D-W., Dalton, P. D., ... Malda, J. (2016). Biofabrication: reappraising the definition of an evolving field. Biofabrication, 8(1), [013001]. https://doi.org/10.1088/1758-5090/8/1/013001
  • Habraken, W., Habibovic, P., Epple, M., & Bohner, M. (2016). Calcium phosphates in biomedical applications: materials for the future? Materials Today, 19(2), 69-87. https://doi.org/10.1016/j.mattod.2015.10.008
  • Birgani, Z. T., van Blitterswijk, C. A., & Habibovic, P. (2016). Monolithic calcium phosphate/poly(lactic acid) composite versus calcium phosphate-coated poly(lactic acid) for support of osteogenic differentiation of human mesenchymal stromal cells. Journal of Materials Science-Materials in Medicine, 27(3), [54]. https://doi.org/10.1007/s10856-016-5666-9
  • Prins, H-J., Fernandes, H., Rozemuller, H., van Blitterswijk, C., de Boer, J., & Martens, A. C. M. (2016). Spatial distribution and survival of human and goat mesenchymal stromal cells on hydroxyapatite and beta-tricalcium phosphate. Journal of Tissue Engineering and Regenerative Medicine, 10(3), 233-244. https://doi.org/10.1002/term.1681
  • Di Luca, A., Longoni, A., Criscenti, G., Lorenzo-Moldero, I., Klein-Gunnewiek, M., Vancso, J., ... Moroni, L. (2016). Surface energy and stiffness discrete gradients in additive manufactured scaffolds for osteochondral regeneration. Biofabrication, 8(1), [015014]. https://doi.org/10.1088/1758-5090/8/1/015014
  • Criscenti, G., Longoni, A., Di Luca, A., De Maria, C., van Blitterswijk, C. A., Vozzi, G., & Moroni, L. (2016). Triphasic scaffolds for the regeneration of the bone-ligament interface. Biofabrication, 8(1), [015009]. https://doi.org/10.1088/1758-5090/8/1/015009
  • Gunnewiek, M. K., Ramakrishna, S. N., di Luca, A., Vancso, G. J., Moroni, L., & Benetti, E. M. (2016). Stem-Cell Clinging by a Thread: AFM Measure of Polymer-Brush Lateral Deformation. Advanced Materials Interfaces, 3(3), [1500456]. https://doi.org/10.1002/admi.201500456
  • Georgiadis, P., Hebels, D. G., Valavanis, I., Liampa, I., Bergdahl, I. A., Johansson, A., ... Kyrtopoulos, S. A. (2016). Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking. Scientific Reports, 6, [20544]. https://doi.org/10.1038/srep20544
  • Baker, M. B., Gosens, R. P. J., Albertazzi, L., Matsumoto, N. M., Palmans, A. R. A., & Meijer, E. W. (2016). Exposing Differences in Monomer Exchange Rates of Multicomponent Supramolecular Polymers in Water. Chembiochem, 17(3), 207-213. https://doi.org/10.1002/cbic.201500606
  • Wu, L., Prins, H-J., Leijten, J., Helder, M. N., Evseenko, D., Moroni, L., ... Karperien, M. (2016). Chondrocytes Cocultured with Stromal Vascular Fraction of Adipose Tissue Present More Intense Chondrogenic Characteristics Than with Adipose Stem Cells. TISSUE ENGINEERING PART A, 22(3-4), 336-348. https://doi.org/10.1089/ten.tea.2015.0269
  • Buitinga, M., Portalska, K. J., Cornelissen, D-J., Plass, J., Hanegraaf, M., Carlotti, F., ... de Boer, J. (2016). Coculturing Human Islets with Proangiogenic Support Cells to Improve Islet Revascularization at the Subcutaneous Transplantation Site. TISSUE ENGINEERING PART A, 22(3-4), 375-385. https://doi.org/10.1089/ten.tea.2015.0317
  • Birgani, Z. T., Gharraee, N., Malhotra, A., van Blitterswijk, C. A., & Habibovic, P. (2016). Combinatorial incorporation of fluoride and cobalt ions into calcium phosphates to stimulate osteogenesis and angiogenesis. Biomedical Materials, 11(1), [015020]. https://doi.org/10.1088/1748-6041/11/1/015020
  • Carlier, A., Brems, H., Ashbourn, J. M. A., Nica, I., Legius, E., & Geris, L. (2016). Capturing the wide variety of impaired fracture healing phenotypes in Neurofibromatosis Type 1 with eight key factors: a computational study. Scientific Reports, 6, [20010]. https://doi.org/10.1038/srep20010
  • Hendrikson, W. J., Zeng, X., Rouwkema, J., van Blitterswijk, C. A., van der Heide, E., & Moroni, L. (2016). Biological and Tribological Assessment of Poly(Ethylene Oxide Terephthalate)/Poly(Butylene Terephthalate), Polycaprolactone, and Poly (L\DL) Lactic Acid Plotted Scaffolds for Skeletal Tissue Regeneration. Advanced Healthcare Materials, 5(2), 232-243. https://doi.org/10.1002/adhm.201500067
  • Reimer, A., Vasilevich, A., Hulshof, F., Viswanathan, P., van Blitterswijk, C. A., de Boer, J., & Watt, F. M. (2016). Scalable topographies to support proliferation and Oct4 expression by human induced pluripotent stem cells. Scientific Reports, 6, [18948]. https://doi.org/10.1038/srep18948
  • Rothuizen, T. C., Damanik, F. F. R., Lavrijsen, T., Visser, M. J. T., Hamming, J. F., Lalai, R. A., ... Rotmans, J. I. (2016). Development and evaluation of in vivo tissue engineered blood vessels in a porcine model. Biomaterials, 75, 82-90. https://doi.org/10.1016/j.biomaterials.2015.10.023
  • Hendrikson, W., Masman-Bakker, W., van Bochove, B., Skolski, J., Eichstadt, J., Koopman, B., ... Rouwkema, J. (2016). Mold-Based Application of Laser-Induced Periodic Surface Structures (LIPSS) on Biomaterials for Nanoscale Patterning. Macromolecular Bioscience, 16(1), 43-49. https://doi.org/10.1002/mabi.201500270
  • Chen, H., Gigli, M., Gualandi, C., Truckenmuller, R., van Blitterswijk, C., Lotti, N., ... Moroni, L. (2016). Tailoring chemical and physical properties of fibrous scaffolds from block copolyesters containing ether and thio-ether linkages for skeletal differentiation of human mesenchymal stromal cells. Biomaterials, 76, 261-272. https://doi.org/10.1016/j.biomaterials.2015.10.071
  • Vrij, E. J., Espinoza, S., Heilig, M., Kolew, A., Schneider, M., van Blitterswijk, C. A., ... Rivron, N. C. (2016). 3D high throughput screening and profiling of embryoid bodies in thermoformed microwell plates. Lab on A Chip, 16(4), 734-742. https://doi.org/10.1039/c5lc01499a
  • Hebels, D., Rasche, A., Herwig, R., van Westen, G. J. P., Jennen, D., & Kleinjans, J. (2016). A Systems Biology Approach for Identifying Hepatotoxicant Groups Based on Similarity in Mechanisms of Action and Chemical Structure. In E. Benfenati (Ed.), In Silico Methods for Predicting Drug Toxicity (1 ed., Vol. 1425, pp. 339-359). (Methods in Molecular Biology). Humana Press. https://doi.org/10.1007/978-1-4939-3609-0
  • Vrij, E. J. (2016). Directed assembly and development of engineered tissues using microwell screening platforms. Maastricht: Maastricht University.
  • Benetti, E. M., Gunnewiek, M. K., van Blitterswijk, C. A., Vancso, G. J., & Moroni, L. (2016). Mimicking natural cell environments: design, fabrication and application of bio-chemical gradients on polymeric biomaterial substrates. Journal of Materials Chemistry. B, Materials for Biology and Medicine, 4(24), 4244-4257. https://doi.org/10.1039/c6tb00947f
  • Leenders, C. M. A., Baker, M. B., Pijpers, I. A. B., Lafleur, R. P. M., Albertazzi, L., Palmans, A. R. A., & Meijer, E. W. (2016). Supramolecular polymerisation in water; elucidating the role of hydrophobic and hydrogen-bond interactions. Soft Matter, 12(11), 2887-2893. https://doi.org/10.1039/c5sm02843d
  • Baiao Barata, D., Resmini, A., Pereira, D., Veldhuis, S. A., van Blitterswijk, C. A., ten Elshof, J. E., & Habibovic, P. (2016). Surface micropatterning with zirconia and calcium phosphate ceramics by micromoulding in capillaries. Journal of Materials Chemistry. B, Materials for Biology and Medicine, 4(6), 1044-1055. https://doi.org/10.1039/c5tb02027a