Samiksha Sardana studied Chemistry at the University of Amsterdam and Leiden University. She obtained her PhD in Chemistry from Utrecht University, where she developed mass-spectrometry-based approaches to study long-chain S-acylation. She then moved to Maastricht to join the MERLN institute as a postdoctoral researcher.

Her research focuses on developing an automated clinical proteomics pipeline to study tissues from osteoarthritic patients. Osteoarthritis is the most common degenerative join disease, affecting more than 600 million people worldwide. However, no therapy currently exists. As this condition consists of multiple endotypes with distinct molecular signatures, identifying these signatures is essential for improving diagnosis and treatment.

By integrating high-throughput proteomics with spatial omics approaches, Samiksha aims to uncover biomarkers that define osteoarthritis endotypes. These insights will support patient stratification for current treatments and contribute to the development of personalised therapeutic strategies.